SOLIRIS (eculizumab): The first treatment specifically approved for PNH

Side Effects

Is SOLIRIS right for me?

In the clinical trials for SOLIRIS® (eculizumab), the most common side effects were

  • Headache
  • Runny nose and colds
  • Back pain
  • Nausea

Side EffectsOverall, the rate of side effects was similar to placebo in clinical trials. The number of headaches that occurred was similar between patients taking SOLIRIS and those on placebo after the first 2 weeks of therapy.

Call your doctor if you are experiencing any of these side effects or have any questions.

Next: Important Safety Information

IMPORTANT SAFETY INFORMATION

WARNING: SERIOUS MENINGOCOCCAL INFECTION

SOLIRIS® increases the risk of meningococcal infections.

Patients should be vaccinated with a meningococcal vaccine at least 2 weeks prior to receiving the first dose of SOLIRIS. Revaccinate according to current medical guidelines for vaccine use.

Patients should be monitored closely for early signs of meningococcal infections and evaluated immediately if infection is suspected, and treated with antibiotics if necessary.

The effect of withdrawal of anticoagulant therapy during SOLIRIS treatment has not been established. Therefore, treatment with SOLIRIS should not alter anticoagulant management.

SEE FULL PRESCRIBING INFORMATION FOR COMPLETE BOXED WARNING INCLUDING WARNINGS, PRECAUTIONS, AND ADVERSE REACTIONS.

The most frequent adverse events observed in clinical studies were headache, nasopharyngitis, back pain, nausea, fatigue, and cough.

Please see important safety information (including boxed warning) as well as the complete prescribing information.