SOLIRIS (eculizumab): The first treatment specifically approved for PNH

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Learn how OneSource can provide additional information about PNH and SOLIRIS.

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Sign up to learn and share. As part of the SOLIRIS® (eculizumab) community, you'll receive regular updates, news and information. If you choose, you can also register to participate in market research activities.

  • Learn more about SOLIRIS as new research is published
  • Discover new PNH resources and support systems
  • Get ideas and tips for living with and managing PNH
  • Stay in touch with developments in PNH research and treatment

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IMPORTANT SAFETY INFORMATION

WARNING: SERIOUS MENINGOCOCCAL INFECTION

SOLIRIS® increases the risk of meningococcal infections.

Patients should be vaccinated with a meningococcal vaccine at least 2 weeks prior to receiving the first dose of SOLIRIS. Revaccinate according to current medical guidelines for vaccine use.

Patients should be monitored closely for early signs of meningococcal infections and evaluated immediately if infection is suspected, and treated with antibiotics if necessary.

The effect of withdrawal of anticoagulant therapy during SOLIRIS treatment has not been established. Therefore, treatment with SOLIRIS should not alter anticoagulant management.

SEE FULL PRESCRIBING INFORMATION FOR COMPLETE BOXED WARNING INCLUDING WARNINGS, PRECAUTIONS, AND ADVERSE REACTIONS.

The most frequent adverse events observed in clinical studies were headache, nasopharyngitis, back pain, nausea, fatigue, and cough.

Please see important safety information (including boxed warning) as well as the complete prescribing information.