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Brochures, Tools, and Publications

To order hard copies of these brochures, tools, and publications log in below or register today. Click here to view the full Prescribing Information.

Brochures and Tools

In order to help you learn more about Soliris^® and PNH, we have developed several brochures. Feel free to view and print a PDF of each of these.

Understanding PNH: A guide for patients and their caregivers A brochure for patients and their caregivers that provides information about PNH.

Understanding Soliris Therapy: A guide for patients with PNH—and their caregivers Patient brochure that provides information on PNH and treatment with Soliris.

Soliris OneSource™ Brochure Brochure outlining OneSource access and treatment support services for patients.

Soliris Patient Safety Information Card Wallet reference card for patients.

Publications

While these articles are intended for physicians, patients may find some of the information helpful. It is recommended that patients either provide a copy to their physician to discuss the findings or note the publication, author, and publication date of the specific article. To order a hard copy of any of these publications, register today. If you are already registered, log in above to order.

Soliris Publications:

Brodsky RA, Young NS, Antonioli E, et al. Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria. Blood. 2008;111:1840-1847.

Hillmen P, Hall C, Marsh JCW, et al. Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria. N Engl J Med. 2004;350:552-559.

Hillmen P, Young NS, Schubert J, et al. The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. N Engl J Med. 2006;355:1233-1243.

Hillmen P, Muus P, Duhrsen U, et al. Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria [published online ahead of print August 16, 2007]. Blood. 2007;110:4123-4128. doi:10.1182/blood-2007-06-095646.

Differential Diagnosis of PNH:

Abou Antoun S, El-Haddad B, Wehbe E, Schulz T. Lysis and thrombosis: manifestation of the same disease. Am J Hematol. 2008;83:505-507.

PNH and Renal Disease:

Clark DA, Butler SA, Braren V, Hartmann RC, Jenkins DE Jr. The kidneys in paroxysmal nocturnal hemoglobinuria. Blood. 1981;57:83-89.

PNH Review Articles:

Hill A, Richards SJ, Hillmen P. Recent developments in the understanding and management of paroxysmal nocturnal haemoglobinuria. Br J Haematol. 2007;137:181-192.

Hillmen P, Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history of paroxysmal nocturnal hemoglobinuria. N Engl J Med. 1995;333:1253-1258.

Parker C, Omine M, Richards S, et al, for the International PNH Interest Group. Diagnosis and management of paroxysmal nocturnal hemoglobinuria. Blood. 2005;106:3699-3709.

Peffault de Latour R, Mary JY, Salanoubat C, et al. Paroxysmal nocturnal hemoglobinuria: natural history of disease subcategories [published online ahead of print June 5, 2008]. Blood. doi:10.1182/blood-2008-01-133918.

PNH and Bone Marrow Disorders:

Maciejewski JP, Rivera C, Kook H, Dunn D, Young NS. Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol-anchored protein-deficient clones. Br J Haematol. 2001;115:1015-1022.