How Will Soliris® Change My Life?
Soliris works by improving your symptoms
You probably have millions of questions about Soliris therapy. Because it works by blocking complement (one of your body’s defense systems), Soliris reduces hemolysis. This will improve your symptoms and reduce major health problems associated with PNH, therefore helping you get back to enjoying life.1
Soliris treats chronic hemolysis — the underlying cause of the signs and symptoms of PNH.1 In clinical trials, patients who received Soliris experienced the following benefits1-3:
- Reduced chronic hemolysis in all patients — immediate and long term
- Fewer blood clots (thrombotic events), as compared to the same time period prior to starting Soliris
- Significant improvements in fatigue levels and overall quality of life
- Significant reduction in the need for transfusions
The majority of patients received concomitant anticoagulant therapy.1 The effect of anticoagulant withdrawal during Soliris treatment has not been studied.1
How to manage PNH with Soliris
Your initial Soliris treatment (induction phase) involves a 600-mg infusion once a week for the first 4 weeks. At Week 5 you will receive a 900-mg infusion every 2 weeks (maintenance phase). It is important to make sure that you do not miss any scheduled treatments in order to continue to control hemolysis and to experience the full benefits of Soliris therapy.1,3,4
Since PNH is a chronic disease, Soliris is intended to be an ongoing therapy.1 Patients who start Soliris should continue receiving Soliris, even if they feel better. If for some reason you and your doctor decide to stop Soliris therapy, only your doctor can safely manage taking you off the drug.