Common Symptoms of Hemolysis Signal the Underlying Threat of Serious and Disabling Consequences
A patient may present with any of the following PNH symptoms, including abdominal pain, dyspnea, or hemoglobinuria. But just like an iceberg hiding its true magnitude beneath the water, these symptoms may be indicative of more serious consequences that lie beneath the surface, such as thrombosis, pulmonary hypertension, or chronic kidney disease.
Reducing chronic hemolysis is the primary goal of PNH management.1,2